![Neratinib (HKI-272) vinostat) 4-triazol-1-yl]phenyl}-4-[3-(morpholin-4-yl)phenyl]pyrimidin-2-amine](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M7845_1619054332.gif?v=1629179424)
Pay in 4 interest-free payments of $20.00 Learn more
Ships within 48 hours · Estimated delivery Jul 31 - Aug 5
4-triazol-1-yl]phenyl}-4-[3-(morpholin-4-yl)phenyl]pyrimidin-2-amine
Solubility: DMSO up to 15 mM
induces apoptosis in primary AML marrow blasts but not in normal myeloblasts
PubMed Central PMCID: PMC3717953
Neratinib (HKI-272) vinostat) 4-triazol-1-yl]phenyl}-4-[3-(morpholin-4-yl)phenyl]pyrimidin-2-amineNeratinib, also known as HKI 272 or PB272, is an orally available, irreversible inhibitor of the HER 2 receptor tyrosine kinase with potential antineoplastic activity. Neratinib binds to the HER 2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently by targeting a cysteine residue in the ATP binding pocket of the receptor. Product information CAS Number: 698387 09 6 Molecular Weight: 557. 04 Formula: C30H29ClN6O3 Synonym:
US$ 22.00
US$ 873.75
US$ 49.99
US$ 34.99